348013
C-X-C motif chemokine 6, active (CXCL6), Recombinant, Human
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£411.00
- SKU:
- 348013
- Molekulargewicht:
- 7.9
- Reinheit:
- ≥98% as determined by SDS-PAGE and HPLC.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Format:
- Lyophilized from 0.2um filtered PBS, pH 7.4
- Weitere Details:
- Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7). {ECO:0000269|PubMed:18443119, ECO:0000269|PubMed:8399143, ECO:0000269|PubMed:8423327, ECO:0000269|PubMed:9057843}. Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration range of 10-50ng/ml. Sequence: VLTELRCTCL RVTLRVNPKT IGKLQVFPAG PQCSKVEVVA SLKNGKQVCL DPEAPFLKKV IQKILDSGNK KN Molecular Weight: 7.9kD PubMed ID: 9164944; 14702039; 15815621; 15489334; 9057843; 8399143; 8423327; 18443119 Gene Name: CXCL6,GCP2,SCYB6 Swiss Prot: P80162 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice