C-C motif chemokine 25, active (Ccl25), Recombinant, Mouse

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£411.00

SKU:: 347964
Molekulargewicht:: 14.1
Reinheit:: ≥95% as determined by SDS-PAGE and HPLC.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Format:: Lyophilized from 0.2um filtered PBS, pH 7.4
Weitere Details:: Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 5.0-50ng/ml. Sequence: QGAFEDCCLG YQHRIKWNVL RHARNYHQQE VSGSCNLRAV RFYFRQKVVC GNPEDMNVKR AIRILTARKR LVHWKSASDS QTERKKSNHM KSKVENPNST SVRSATLGHP RMVMMPRKTN N Molecular Weight: 14.1kD PubMed ID: 9285413; 10602049; 16517733; 16141072; 19468303; 15489334 Gene Name: Ccl25,Scya25,Teck Swiss Prot: O35903 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.