347960
C-C motif chemokine 23, active (CCL23), Recombinant, Human
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£411.00
- SKU:
- 347960
- Molekulargewicht:
- 11.4
- Reinheit:
- ≥97% as determined by SDS-PAGE and HPLC.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Format:
- Lyophilized from 0.2um filtered PBS, pH 7.4
- Weitere Details:
- Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23. {ECO:0000269|PubMed:15905581}. Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 10-50ng/ml. Sequence: RVTKDAETEF MMSKLPLENP VLLDRFHATS ADCCISYTPR SIPCSLLESY FETNSECSKP GVIFLTKKGR RFCANPSDKQ VQVCMRMLKL DTRIKTRKN Molecular Weight: 11.4kD PubMed ID: 9104803; 9558365; 10213461; 16625196; 15489334; 9129202; 15905581; 11060285 Gene Name: CCL23,MIP3,MPIF1,SCYA23 Swiss Prot: P55773 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice