347956
C-C motif chemokine 21, active (CCL21), Recombinant, Human
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£411.00
- SKU:
- 347956
- Molekulargewicht:
- 12.2
- Reinheit:
- ≥97% as determined by SDS-PAGE and HPLC.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Format:
- Lyophilized from 0.2um filtered PBS, pH 7.4
- Weitere Details:
- Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human lymphocytes is in a concentration range of 10-100ng/ml. Sequence: SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCK RTERSQTPKG P Molecular Weight: 12.2kD PubMed ID: 9235955; 9257816; 9300671; 9419363; 12975309; 15489334; 9507024; 23341447; 22221265 Gene Name: CCL21,SCYA21,UNQ784/PRO1600 Swiss Prot: O00585 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice