347945
C-C motif chemokine 14, active (CCL14), Recombinant, Human
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£518.00
- SKU:
- 347945
- Molekulargewicht:
- 8.4
- Reinheit:
- ≥96% (SDS-PAGE and HPLC)
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Format:
- Lyophilized from 0.2um filtered PBS, pH 7.4
- Weitere Details:
- Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induced intracellular Ca(2+) changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and was inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5. {ECO:0000269|PubMed:11085751}. Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration of 5.0-20ng/ml. Sequence: TESSSRGPYH PSECCFTYTT YKIPRQRIMD YYETNSQCSK PGIVFITKRG HSVCTNPSDK WVQDYIKDMK EN Molecular Weight: 8.4kD PubMed ID: 8551235; 9600961; 10213461; 15489334; 10978165; 11085751; 17691823 Gene Name: CCL14, NCC2, SCYA14 Swiss Prot: Q16627 Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice