SLC39A3

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£460.00

SKU:: 334613
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide of human SLC39A3
Format:: Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
Weitere Details:: SLC39A3 (solute carrier family 39, member 2), is a 314aa acid multi-pass membrane protein that localizes to the cell membrane and belongs to the ZIP family of zinc transporters. Two isoforms of ZIP3 exist as a result of alternative splicing events. ZIP3 is involved in translocation of extracellular zinc into a variety of cell types. Tumorigenic prostate epithelial cells contain less intracellular zinc than non-tumorigenic prostate epithelial cells. Loss of the ability to maintain zinc accumulation may be caused by the decrease in the ZIP1 protein expression and the intracellular redistribution of ZIP3. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1000-1:2000 Immunohistochemistry: 1:25-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.