323221
MARCKSL1 (MARCKS-like Protein 1, Macrophage Myristoylated Alanine-rich C Kinase Substrate, MLP, MRP)
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£800.00
- SKU:
- 323221
- Reinheit:
- Purified by immunoaffinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Human Marcksl1. Species sequence homology: mouse
- Format:
- Supplied as a liquid in PBS, pH 7.3, 0.09% sodium azide, 50% glycerol.
- Weitere Details:
- MARCKS (Myristoylated alanine-rich protein kinase C substrate), also designated 80K or 80K-L, is a 332aa protein that localizes to the plasma membrane and functions as a major cellular substrate for protein kinase C (PKC). MARCKSL1 (MARCKS-like protein 1), also known as MacMARCKS, MLP, MRP, or F52, is a 195aa protein that, like MARCKS, is a major substrate for PKC. Expressed in a variety of tissues with highest levels found in testis and uterus, MARCKSL1 participates in the coordination of membrane-cytoskeletal signaling events, including secretion, migration, phagocytosis and cell adhesion. Additionally, MARCKSL1 functions as a regulator of Integrin activation and is thought to regulate Integrin-dependent signal transduction pathways, especially those involved in macrophage spreading. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice