322184
LPHN1 (Latrophilin-1, Calcium-independent alpha-latrotoxin Receptor 1, CIRL-1, Lectomedin-2, KIAA0821, LEC2)
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£364.00
- SKU:
- 322184
- Reinheit:
- Purified by immunoaffinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to the Internal region of human Latrophilin-1.
- Format:
- Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
- Weitere Details:
- The Latrophilin family of G protein-coupled receptors consists of three members, latrophilin-1, 2 and 3, each of which displays distinct tissue distribution and function. Latrophilin-1, the most characterized member of this family, acts as a receptor for a-latrotoxin, a component of venom from the black widow spider. Binding of a-latrotoxin to latrophilin-1 triggers synaptic vesicle exocytosis via both Ca2+-dependent and -independent mechanisms, resulting in vesicle depletion. Latrophilin-1 is abundant in brain and present in endocrine cells. Latrophilin-3 is also brain-specific, whereas latrophilin-2 expression is ubiquitous. Applications: Suitable for use in Immunofluorescence and ELISA. Other applications not tested. Recommended Dilution: Immunofluorescence: 1:200-1:1000 ELISA: 1:5000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice