Eotaxin (C-C Motif Chemokine 11, CCL 11, CCL11, Chemokine (C-C Motif) Ligand 11, Chemokine C C Motif Ligand 11, Chemokine CC Motif Ligand 11, Chemokine Ligand 11, Eosinophil Chemotactic Protein, Eotaxin-1, SCYA 11, SCYA11, Small Inducible Cytokine A11, Small Inducible Cytokine Subfamily A (Cys Cys) Member 11, Small Inducible Cytokine Subfamily A (Cys-Cys), Member 11 (Eotaxin), Small Inducible Cytokine Subfamily A Member 11, Small-inducible Cytokine A11)

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£620.00

SKU:: 303295
Anwendung:: WB
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to mouse Eotaxin expressed in E. coli. (Position: H24-P97). Species sequence homology: human (62%) and rat (97%)
Format:: Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% sodium azide. Reconstitute with 200ul sterile dH2O.
Weitere Details:: CCL11, also known as Eotaxin, is a potent inducer of eosinophil chemotaxis and is considered as a selective ligand of the CC chemokine receptor 3 (CCR3), which is expressed on eosinophils, basophils, and Th2 lymphocytes. The gene maps to chromosome 17 and is expressed constitutively at high levels in small intestine and colon, and at lower levels in various other tissues. CCL11 is a small cytokine belonging to the CC chemokine family. It is assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.1-0.5ug/ml, the detection limit is ~0.25ng/lane under reducing conditions. Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Versandbedingungen:: Blue Ice