Amyloid beta, CT (A4, AAA, ABETA, ABPP, AD1, AICD-50, AICD-57, AICD-59, AID(50), AID(57), AID(59), Alzheimer Disease Amyloid Protein, Alzheimers Disease Amyloid Protein, Amyloid B, Amyloid beta (A4) Precursor Protein, Amyloid beta A4 Protein, Amyloid Beta A4 Protein Precursor, Amyloid Intracellular Domain 50, Amyloid Intracellular Domain 57, Amyloid Intracellular Domain 59, Amyloid of Aging and Alzheimer Disease, APP, APPI, B Amyloid, Beta APP, Beta-amyloid Peptide, Beta-APP40, Beta-APP42, C31, Cerebral Vascular Amyloid Peptide, CTFgamma, CVAP, Gamma-CTF(50), Gamma-CTF(57), Gamma-CTF(59), Peptidase Nexin-II, PN II, PN-II, PN2, PreA4, Protease Nexin II, Protease Nexin-II, S-APP-alpha, S-APP-beta)

Größe

£620.00

SKU:: 303112
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to aa672-713, DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA, from human beta Amyloid at C-terminus, different from the related mouse and rat sequences by 3aa.
Format:: Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% sodium azide. Reconstitute with 200ul sterile dH2O.
Weitere Details:: Beta Amyloid, also called Ab or Abeta, denotes peptides of aa36-43 that are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer patients. It is mapped to 19q13.12. Several potential activities have been discovered for beta Amyloid, including activation of kinase enzymes, functioning as atranscription factor, and anti-microbial activity (potentially associated with beta Amyloid's pro-inflammatory activity). Moreover, monomeric beta Amyloid is indicated to protect neurons by quenching metal-inducible oxygen radical generation and thereby inhibiting neurotoxicity. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.1-0.5ug/ml, the detection limit is ~0.25ng/lane under reducing conditions. Immunohistochemistry (paraffin): 0.5-1ug/ml, boiling the paraffin sections in 10mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections. Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Versandbedingungen:: Blue Ice