SAP14 (Splicing Factor 3B Subunit 6, Pre-mRNA branch Site Protein p14, SF3b 14kD Subunit, SF3B14a, Spliceosome-Associated Protein, 14-kDa, Splicing Factor 3b, Subunit 6, 14kDa, SF3B6, SAP14, SF3B14, SF3B14A)

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£633.00

SKU:: 302727
Anwendung:: WB
Reinheit:: Purified
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: KLH conjugated synthetic peptide corresponding to human SAP14.
Format:: Supplied as a liquid in 0.01M PBS, pH 7.2, 0.09% sodium azide, 50% glycerol.
Weitere Details:: Necessary for the splicing of pre-mRNA. Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing. Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.