302694
RAPGEF1 (Rap Guanine Nucleotide Exchange Factor 1, CRK SH3-Binding GNRP, Guanine Nucleotide-Releasing Factor 2, Protein C3G, RAPGEF1, GRF2)
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£696.00
- SKU:
- 302694
- Anwendung:
- WB
- Reinheit:
- Purified by Protein A affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- KLH conjugated synthetic peptide corresponding to aa536-569 at the Central region of human RAPGEF1.
- Format:
- Supplied as a liquid in PBS, 0.09% sodium azide.
- Weitere Details:
- Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:2000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice