PPP2R5B (Serine/Threonine-Protein Phosphatase 2A 56kD Regulatory Subunit beta isoform, PP2A B Subunit isoform B'-beta, PP2A B Subunit isoform B56-beta, PP2A B Subunit isoform PR61-beta, PP2A B Subunit isoform R5-beta, PPP2R5B)

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£696.00

SKU:: 302665
Reinheit:: Purified by Protein A affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: KLH conjugated synthetic peptide corresponding to aa466-500 at the C-terminal region of human PPP2R5B.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Weitere Details:: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The phosphorylated form mediates the interaction between AKT1 and PP2A phosphatase leading to dephosphorylation of AKT1 on the 'Thr-308' and 'Ser-373' residues. Applications: Suitable for use in Immunofluorescence, Western Blot. Other applications not tested. Recommended Dilution: Immunofluorescence: 1:25 Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.