NR4A2 (Nurr1, Nuclear Receptor Related 1, Nuclear Receptor Subfamily 4, Group A, Member 2, Nurr 1, Nurr-1)

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£678.00

SKU:: 301432
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to amino acids from an internal sequence, TERHGLKEPKRVEE of human NR4A2.
Format:: Supplied as a liquid in PBS, 0.02% sodium azide.
Weitere Details:: The Nurr1 gene encodes a member of the steroid-thyroid hormone- retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson's. Nurr1 is a stem cell marker and cooperates with PITX3 to promote terminal maturation of mouse and human embryonic stem cell cultures to a midbrain dopamine neuron phenotype. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.