298114
Advanced Glycosylation Endproduct (AGE, Ne-Carboxymethyllysine, CML, N(6)-Carboxymethyllysine)
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£364.00
- SKU:
- 298114
- Reinheit:
- Purified by immunoaffinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Goat
- Immunogen:
- N_x000F_-(carboxymethyl) lysine, KLH conjugated
- Format:
- Supplied as a lyophilized powder in 75mM PBS, pH 7.2, 75mM sodium chloride, 0.5mM EDTA, 0.02% sodium azide. Reconstitute with sterile ddH2O.
- Weitere Details:
- Recognizes a variety of advanced glycated end product (AGE) epitopes. Glycation is the post-translational modification of proteins, linking a reducing sugar to an amino group on a protein. AGEs are thought to be involved in structural and functional alterations of proteins observed in aging and diabetes. AGEs recognised include carboxymethyllysine and pentosidine. Increases in pentosidine levels are associated with aging, diabetes, cataracts, renal diseases, chronic rheumatoid arthritis, photaged skin and Alzheimers disease. Carboxymethyllysine is involved in uracemia. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:200-1:20,000 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice