298069
Ficolin-2 (Ficolin-2/P35, L-Ficolin, Ficolin L, EBP-37, Hucolin)
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£1,138.00
- SKU:
- 298069
- Reinheit:
- Purified by Protein G affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Klon:
- GN4
- Format:
- Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
- Weitere Details:
- The monoclonal antibody Ficolin-2 recognizes human Ficolin-2, also known as L-ficolin. Ficolins are a family of pattern recognition molecules containing both a collagen-like domain and a fibrinogen-like domain that are capable of activating the complement system, through association with MASPs, on the surface of microorganisms. In human, three Ficolins are known: Ficolin-1 (M-ficolin), Ficolin-2 (L-ficolin), and Ficolin-3 (H-ficolin). Ficolin-1, is mainly expressed by monocytes, granulocytes and lung cells and is present locally in areas of inflammation. Ficolin-2 (also L-ficolin, ficolin L, EBP-37 or hucolin) is produced primarily by the liver. The association between Ficolin-2 and MASPs/sMAP is Ca2+-dependent. MASPs in Ficolin-2- MASP complexes have proteolytic activities for C4, C2 and C3. Ficolin-2 also shows opsonic activity. Applications: Suitable for use in ELISA, Immunoprecipitation, Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:50 Immunohistochemistry(Frozen): 1:50 Immunoprecipitation: 1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice