GM1-Pentasaccharide

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£403.00

SKU:: 297646
Molekulargewicht:: 998.88
Reinheit:: ≥95%
Lagerbedingungen:: 4°C
Hersteller:: United States Biological
CAS Number:: 52659-37-7
Format:: White to off-white powder
Weitere Details:: Oligosaccharide domain of the monosialylated glycosphingolipid GM1, which is a major ganglioside in neuronal and glial membranes in the central nervous system. GM1 oligosaccharide interacts and modulates tyrosine kinases such as neural tropomyosin receptor kinase A (TrkA) and the epidermal growth factor receptor (EGFR). The compound is also found in epithelial membranes and is a key element for bacterial toxicity and viral infection since it acts as a receptor for the B-subunits of heat labile toxin, cholera toxin, rotavirus, and simian virus 40. It also has the ability to bind amyloid-β proteins and is involved in Alzheimer’s pathogenesis. Synonyms: GM1-oligosaccharide CAS No: 52659-37-7 Molecular Formula: C37H62N2O29 Molecular Weight: 998.88 Appearance: White to off-white powder Purity: ≥95% Storage: 4°C