Posaconazole

Größe

£397.00

SKU:: 286988
Molekulargewicht:: 700.78
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
CAS Number:: 171228-49-2
Weitere Details:: Anti-fungal agent; sterol α-demethylase inhibitor. Posaconazole is a highly potent broadspectrum antifungal drug. It blocks the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase resulting in accumulation of methylated sterol precursors. In contrast to other antifungal azoles, posaconazole has been reported not to induce the efflux pump mechanism. Posaconazole was able to produce a parasitological cure in a mouse model of the chronic stage of Chagas disease. Synonyms: 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol; Noxafil; Sch 56592 CAS No: 171228-49-2 Molecular Formula: C₃₇H₄₂F₂N₈O₄ Molecular Weight: 700.78 Purity: ≥98% Appearance: White to off-white powder Melting Point: 166-168°C (lit) Specific Rotation (C=1 CHCL3): As Reported Storage and Stability: Store at -20ºC. Stable for 6 months after receipt.