N-(2-(Diethylamino)ethyl)-5-((Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide

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£314.00

SKU:: 273137
Molekulargewicht:: 398.47
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
CAS Number:: 557795-19-4
Weitere Details:: Sunitinib (as the malate salt) is the active ingredient in the drug sold under the trade name Sutent. This drug is a small molecule receptor tyrosine kinase inhibitor that has been approved in at least one country for the treatment of patients having gastrointestinal stromal tumors or renal cell carcinomas. Synonyms: N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide; SU-11248; Sutent; PHA-290940AD; PNU-290940AD CAS No: 557795-19-4 Molecular Formula: C22H27FN4O2 Molecular Weight: 398.47 Appearance: Yellow powder Purity: ≥99% Solubility: Soluble Solubility: Soluble Solubility: Soluble in DMSO at 40mg/ml; soluble in ethanol at 1.4mg/ml with warming; very poorly soluble in water; maximum solubility in plain water is estimated to be about 10-20uM; buffers, serum, or other additives may increase or decrease the aqueous solubility. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.