Validamycin A

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£316.00

SKU:: 257416
Molekulargewicht:: 497.49
Reinheit:: ≥64%
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
CAS Number:: 37248-47-8
Format:: Off-white to yellow powder
Weitere Details:: An inhibitor of trehalase. Validamycin A is an antifungal agent used to protect rice plants against sheath blight caused by the pathogenic fungus, R. solani, due to its ability to inhibit trehalase, a trehalose-hydrolizing enzyme (Ki = 1.9nM; IC50 = 0.7uM).1 It is also effective against the growth and sporulation of R. cerealis, F. culmorum, and other fungi.2 This compound has also been used to study trehalase activity and trehalose biosynthesis.3 Synonyms: 1,5,6-Trideoxy-4-O-β-D-glucopyranosyl-5-(hydroxymethyl)-1-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-D-chiro-inositol; Cepex 10SL; Jinganmycin A; Jinggang; Jinggangmycin; Jinggangmycin A; Validacin; Validamycin; Validamycin A; [1S-(1α,4α,5β,6α)]-1,5,6-Trideoxy-4-O-β-D-glucopyranosyl-5-(hydroxymethyl)-1-[[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-D-chiro-inositol CAS No: 37248-47-8 Molecular Formula: C20H35NO13 Molecular Weight: 497.49 Appearance: Off-white to yellow powder Purity: ≥64% pH: 2.5-5.0 Water: ≤5% Water Insoluble: ≤0.2% Solubility: DMSO, Methanol (Slightly), Water (Slightly) Storage: -20°C. Hygroscopic, Under inert atmosphere