Ro 25-6981 maleate

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£288.00

SKU:: 256479
Molekulargewicht:: 455.55
Reinheit:: ≥98% (HPLC)
Lagerbedingungen:: RT
Hersteller:: United States Biological
CAS Number:: 1312991-76-6
Format:: White solid
Weitere Details:: Potent and selective activity-dependent blocker of NMDA receptors containing the NR2B subunit. IC50 values are 0.009 and 52 μM for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A respectively. Displays neuroprotectant effects in vivo and in vitro. Synonyms: (αR,βS)-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate CAS Number: 1312991-76-6 Molecular Formula: C22H29NO2.C4H4O4 Molecular Weight: 455.55 Appearance: White solid Purity: ≥98% (HPLC) TLC: Rf = 0.68 (Dichloromethane:Methanol:NEt3 [90:9:1]) Chiral HPLC: Shows 100% purity 1H NMR: Consistent with structure Mass Spectrum: Consistent with structure Optical Rotation: [α]D = +19.7 (Concentration = 1, Solvent = Methanol) Microanalysis: Carbon Hydrogen Nitrogen Theoretical 68.55 7.3 3.07 Found 68.18 6.97 3.21 Solubility: DMSO: 45.55 100mM Water: 4.56 10mM with gentle warming Storage: Desiccate at RT