Alendronate sodium (MK 217)

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£306.00

SKU:: 255832
Molekulargewicht:: 271.08
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
CAS Number:: 129318-43-0
Weitere Details:: Osteoclast-mediated bone resorption inhibitor. Binds and blocks farnesyl diphosphate synthase (FPPS) in the HMG-CoA pathway (IC50 = 460nM for recombinant human FPPS); causes macrophage apoptosis. Inhibits prenylation and sterol biosynthesis in purified osteoclasts. Solubility: 50mM in water