A 438079 hydrochloride

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SKU:: 254470
Molekulargewicht:: 342.61
Reinheit:: ≥98% (HPLC
Lagerbedingungen:: 4°C
Hersteller:: United States Biological
CAS Number:: 899431-18-6
Weitere Details:: Competitive P2X7 receptor antagonist (pIC50 = 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line). Devoid of activity at other P2 receptors (IC50 >> 10 μM). Possesses antinociceptive activity in models of neuropathic pain in vivo. Inhibits methamphetamine-induced microglial migration and phagocytosis in vitro. Alternate Name: 3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine Monohydrochloride; 3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine Monohydrochloride; A 438079 CAS Number: 899431-18-6 Molecular Formula: C₁₃H₁₀Cl₃N₅ Molecular Weight: 342.61 Purity: ≥98% (HPLC)