Kallikrein 2 (Hk2, hK2, KLK2A 2, KLK2A2, Tissue kallikrein 2, Glandularkallikrein 2, hGK 1, Kallikrein 2 Prostatic, KLK 2, MGC12201)

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£731.00

SKU:: 254127
Reinheit:: Purified by Protein G affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Line tumor cells expressing hK2
Klon:: 6B7
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Weitere Details:: Kallikreins (KLKs) are a subgroup of trypsin-like serine proteases and are implicated in carcinogenesis. Kallikrein 2 is most closely related to Kallikrein 3 (PSA) with 78 identity and with kallikrein 1 at 68 identity. Like Kallikrein 3 Kallikrein 2 is found in greatest abundance in the prostate but at much lower levels than Kallikrein 3. In addition Kallikrein 2 seems to be more labile than Kallikrein 1 or Kallikrein 3 and is often found in a cleaved form. Kallikrein 2 is inhibited by Protein C Inhibitor (PCI). Applications: Suitable for use in ELISA, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry(Paraffin): 18ug/ml for sections. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.