hnRNP A2B1 (Heterogeneous Nuclear Ribonucleoprotein A2, Heterogeneous Nuclear Ribonucleoprotein A2/B1, Heterogeneous Nuclear Ribonucleoprotein B1, Heterogeneous Nuclear Ribonucleoproteins A2/B1, hnRNP A2, hnRNP A2 / hnRNP B1, hnRNP B1, hnRNP-A2, hnRNP-B1, hnRNPA2, hnRNPB1, HNRPA2, HNRPA2B1, HNRPB1, NuclearRibonucleoprotein particle A2 Protein, RNP A2, RNP B1, RNP-A2, RNP-B1, RNPA2, RNPB1, SNRPB1)

Größe

£731.00

SKU:: 254100
Reinheit:: Purified by Protein A affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Bacterially expressed His-hnRNP-A2 fusion protein (Human)
Klon:: DP3B3
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Weitere Details:: This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. Applications: Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1500-1:6000. Detects a band of ~37kD (predicted molecular weight: 37kD) Immunohistochemistry(Frozen): 1:100. PubMed: 17067748Fix with acetone Immunohistochemistry(Paraffin): 1ug/ml Optimal dilutions to be determined by the researcher. Hybridoma: Sp2/0 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Versandbedingungen:: Blue Ice