Eme1 (6820428D13, Crossover Junction Endonuclease EME1, EC 3.1.22.-Eme1 essential Meiotic Endonuclease 1 Homolog 1 (S. pombe), EME1, S. pombe, Homolog of, 1, essential Meiotic Endonuclease 1 Homolog 1 (S pombe), Essential Meiotic Endonuclease 1 Homolog 1, essential Meiotic Endonuclease 1 Homolog 2, Essential Meiotic Endonuclease 1, S. pombe, Homolog of, 1, FLJ31364hMMS4Homolog of yeast EME1 Endonuclease, MGC106543, MMS4, MMS4 Homolog, MMS4L, MSM4)

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£563.00

SKU:: 254029
Anwendung:: WB
Reinheit:: Purified by Protein A affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Human Eme1 (60-65Kd)
Klon:: 7h2/1
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Weitere Details:: EME1 complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein (MUS81) to form an endonuclease complex which cleaves branched DNA structures, especially those arising during stalled DNA replication. The protein may be involved in repairing DNA damage and in maintaining genomic stability. It interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. Alternative splicing results in multiple transcript variants. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Hybridoma: Sp2/0-Ag.14 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.