227609
DAOA (D-Amino Acid Oxidase Activator, Protein G72, G72) (FITC)
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£576.00
- SKU:
- 227609
- Anwendung:
- FLISA
- Reinheit:
- Purified by Protein G affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to human DAOA.
- Format:
- Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with fluorescein isothiocyanate (FITC).
- Weitere Details:
- D-amino acid oxidase (DAAO) metabolizes exogenous D-amino acids that accumulate during aging and modulates the level of D-serine in the brain, acting as a detoxifying agent. DAAO is specific for the D-configuration of amino acids and exhibits a preference for those with small, hydrophobic side chains and polar, aromatic and basic functional groups. D-amino acid oxidase activator (G72) associates with and activates DAAO. This 157 amino acid protein localizes to the Golgi apparatus. The gene encoding for the protein, known as DAOA, maps to chromosome 13q33.2-13q34. G72 is expressed in amygdala, spinal cord and testis. The G72 protein, together with the associated protein DAAO, is often implicated in schizophrenia. An overexpression of the G72 protein can be detected in schizophrenic brain samples. Applications: Suitable for use in FLISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice