223576
IL-8 (Interleukin-8, IL-8, C-X-C Motif Chemokine 8, Emoctakin, Granulocyte chemotactic Protein 1, GCP-1, Monocyte-derived neutrophil chemotactic Factor, MDNCF, Monocyte-derived neutrophil-Activating peptide, MONAP, Neutrophil-Activating Protein 1, NAP-1 Protein 3-10C, T-Cell chemotactic Factor, CXCL8, IL8)
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£672.00
- SKU:
- 223576
- Reinheit:
- Purified by immunoaffinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to aa21-70 of human IL-8.
- Format:
- Supplied as a liquid PBS, pH 7.2, 0.02% sodium azide, 50% glyceerol.
- Weitere Details:
- IL-8 has been shown to function as a potent neutrophil chemostatic and activating peptide and is an important mediator of inflammatory diseases. Two distinct human IL-8 receptors, designated IL-8RA and IL-8RB, have been characterized. Both are expressed at a high level on neutrophils, and to a lesser extent on monocytes and myeloid cell lines. In addition, the IL-8RA subunit is expressed in T cells such as the Jurkat cell line. Both IL-8Rs are members of the seven-transmembrane domain rhodopsin superfamily of receptors and as such, couple G proteins for signal transduction. The two receptors share 77% amino acid identity. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:500-1:1000 Immunohistochemistry (Paraffin: 1:50-1:200 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice