219865
IFN-omega, Recombinant, Human (Interferon omega, IFN alpha II-1, IFNW1)
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£448.00
- SKU:
- 219865
- Molekulargewicht:
- 19.9
- Reinheit:
- ≥98% (SDS-PAGE and HPLC). Endotoxin: ≤1EU/ug
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Format:
- Supplied as a lyophilized powder. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml Do not vortex. It is recommended that further dilutions be made in PBS, 0.1% BSA or HSA.
- Weitere Details:
- IFN-omega is a type I interferon, which can be induced by virus-infected leukocytes. Members of the type I interferon family, which includes IFN-a, IFN-b, and IFN-omega, signal through IFNAR-1/IFNAR-2 receptor complex, and exert antiviral and antiproliferative activities. IFN-omega exhibits about 75% sequence homology with IFN-a, and contains two conserved disulfide bonds, which are necessary for full biological activity. Recombinant protein corresponding to 172aa residues from human IFN-omega, expressed in E. coli. Molecular Weight: ~19.9kD Biological Activity: The ED50 was determined by a cytotoxicity assay using Human TF-1 cells is ≤0.01ng/ml, corresponding to a specific activity of ≥1x10e8 units/mg. Amino Acid Sequence: CDLPQNHGLL SRNTLVLLHQ MRRISPFLCL KDRRDFRFPQ EMVKGSQLQK AHVMSVLHEM LQQIFSLFHT ERSSAAWNMT LLDQLHTGLH QQLQHLETCL LQVVGEGESA GAISSPALTL RRYFQGIRVY LKEKKYSDCA WEVVRMEIMK SLFLSTNMQE RLRSKDRDLG SS Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. It is recommended that further dilutions be made in PBS, 0.1% BSA or HSA. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice