TIAL1, Recombinant, Human, aa1-375, His-Tag (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1)

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£512.00

SKU:: 218631
Molekulargewicht:: 44
Reinheit:: ≥90% (SDS-PAGE)
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Format:: Supplied as a liquid in PBS, pH 7.4, 2mM DTT, 1mM EDTA, 50% glycerol.
Weitere Details:: TIAL1 is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing. Source: Recombinant protein corresponding to aa1-375 from human TIAL1, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~44kD (398aa), confirmed by MALDI-TOF Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.