217872
Vigabatrin (GABA Transaminase Inhibitor, Vigabatrin, gamma-Vinyl-GABA, Sabril, 4-Amino-5-hexenoic Acid)
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£351.00
- SKU:
- 217872
- Reinheit:
- ≥99% (HPLC)
- Lagerbedingungen:
- 4°C
- Hersteller:
- United States Biological
- CAS Number:
- 68506-86-5
- Format:
- Supplied as a white solid.
- Weitere Details:
- A selective, irreversible inhibitor of GABA transaminase with antiepileptic properties. Covalently binds to the active site of GABA tansaminase to inactivate it in a dose-dependent manner and increases extracellular GABA levels in the brain. Rapidly absorbed following oral administration and is shown to inhibit [3H]GABA uptake across the apical membrane of Caco-2 cell monolayers in a concentration-dependent manner (IC50 = 2.9mM). Synonyms: Vigabatrin, 4-Amino-5-hexenoic acid, GABA Transaminase Inhibitor, Vigabatrin, γ-Vinyl-GABA, Sabril CAS No: 68506-86-5 Molecular Formula: C6H11NO2 Molecular Weight: 129.16 Solubility: H2O: 100mM Primary Target: GABA Transaminase Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice