RS 102895 Hydrochloride (1’-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4’-piperidin]-2(1H)-one Hydrochloride, RS 102895, RS102895)

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£395.00

SKU:: 217756
Molekulargewicht:: 426.86
Reinheit:: ≥98% (HPLC)
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
CAS Number:: 300815-41-2
Format:: Supplied as an off-white powder.
Weitere Details:: A selective antagonist for CCR2 receptors (IC50 = 0.36 and 17.8uM for CCR2b and CCR1 receptors, respectively). Blocks monocyte chemoattractant protein-1 induced calcium influx and chemotaxis (IC50 = 32nM and 1.7uM respectively). A potential anti-inflammatory therapeutic agent by Inhibiting alpha1A, alpha1D and 5-HT1A receptors. Synonyms: 1ʹ-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4ʹ-piperidin]-2(1H)-one hydrochloride, RS 102895, RS102895 CAS Number: 300815-41-2 Formula: C21H21F3N2O2•HCl Solubility: DMSO Appearance: Supplied as an off-white powder. Primary Target: CCR2 Primary Target IC50: 0.36 and 17.8uM for human recombinant CCR2b and CCR1 receptors, respectively. Molecular Weight: 426.86 Storage and Stability: Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.