217297
CXCR2 Antagonist, Cpd 19 (CXCR2 Inhibitor, 3-(2-(cyclopentylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide)
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£386.00
- SKU:
- 217297
- Molekulargewicht:
- 343.38
- Reinheit:
- ≥95% (HPLC)
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- CAS Number:
- 473728-67-5
- Format:
- Supplied as an off-white solid.
- Weitere Details:
- A cell-permeable, cyclobutenedione derivative that acts as a potent antagonist of chemokine receptor CXCR2 (IL8RB) (IC50 = 8nM). Reported to inhibit CXCR2-mediated chemotaxis in a CXCR2 expressing cell line (IC50 = 145nM). Exhibits good stability in human and rat liver microsomal preparations (>50% remaining after 30 min at 37°C). CAS Number: 473728-67-5 Formula: C₁₈H₂₁N₃O₄ Molecular Weight: 343.38 Solubility: DMSO (50mg/ml, light brown solution) Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice