217250
Casein Kinase I Inhibitor III, PF-4800567
Größe
£499.00
- SKU:
- 217250
- Molekulargewicht:
- 359.8
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- CAS Number:
- 1188296-52-7
- Weitere Details:
- PF-4800567 is a selective inhibitor of casein kinase 1ε (CK1ε; IC50 = 32 nM) with greater than 20-fold selectivity over CK1δ. It blocks CK1ε-mediated PER3 nuclear localization and PER2 degradation, both of which are proteins important for maintaining circadian rhythms in cells. PF-4800567 has been used in the study of the CK1 enzymes in the regulation of circadian rhythm and is also reported to have neuroprotective effects. Synonyms: 3-[(3-chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine CAS No: 1188296-52-7 Molecular Formula: C₁₇H₁₈ClN₅O₂ Molecular Weight: 359.8 Purity: ≥99% Appearance: Crystalline solid Storage and Stability: Storage at -20°C under inert gas. Light sensitive.
- Versandbedingungen:
- Blue Ice