BzATP Triethylammonium Salt (2’(3’)-O-(4-Benzoylbenzoyl)adenosine-5’-triphosphate tri(triethylammonium) Salt, P2X7 Purinergic Receptor Agonist, BZATP, 2 ,3 -O-(4-benzoylbenzoyl)ATP, P2X Purinergic Receptor Agonist, BZATP)

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SKU:: 217234
Reinheit:: ≥98% (HPLC)
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
CAS Number:: 112898-15-4
Format:: Supplied as a white solid.
Weitere Details:: A prototypic P2X7 purinergic receptor agonist that exhibits about 3-fold higher agonistic potency for induction of nucleotide channels than ATP (EC50 = 15uM vs 50uM). Serves as a photo-affinity analog of ATP. Its agonistic activity is significantly reduced in the presence of serum albumin. Can serve as a substrate analog for submitochondrial particle ATPase activity (Km = 940uM). Induces a dose-dependent decrease in wild-type murine neural progenitor cell viability and an increase in caspase-3 activity. These effects are not observed in P2X7-/- mice. Synonyms: 2ʹ(3ʹ)-O-(4-Benzoylbenzoyl)adenosine-5ʹ-triphosphate tri(triethylammonium) salt, P2X7 Purinergic Receptor Agonist, BZATP, 2 ,3 -O-(4-benzoylbenzoyl)ATP, P2X Purinergic Receptor Agonist, BZATP CAS Number: 112898-15-4 Molecular Formula: C₂₄H₂₄N₅O₁₅P₃•3C₆H₁₅N Solubility: H2O Form: Supplied as a white solid. Purity: ≥98% (HPLC) Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

BzATP Triethylammonium Salt (2’(3’)-O-(4-Benzoylbenzoyl)adenosine-­5’-triphosphate tri(triethylammonium) Salt, P2X7 Purinergic Receptor Agonist, BZATP, 2 ,3 -O-(4-benzoylbenzoyl)ATP, P2X Purinergic Receptor Agonist, BZATP)