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217010

TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily Member 10b, TRAIL R2)

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£704.00

SKU:
217010
Reinheit:
Purified by Protein G affinity chromatography from culture supernatant.
Lagerbedingungen:
-20°C
Hersteller:
United States Biological
Host:
Rat
Immunogen:
Recombinant protein corresponding to mouse TNFRSF10B.
Klon:
14L913
Format:
Supplied as a lyophilized powder in PBS. Reconstitute with 200ul sterile PBS.
Weitere Details:
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. (provided by RefSeq, Mar 2009) Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:250-1:1000 Immunohistochemistry(Frozen): 1:50-1:200 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Versandbedingungen:
Blue Ice