TGFR-I (Transforming Growth Factor beta Receptor 1, ALK-5)

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£704.00

SKU:: 216989
Reinheit:: Purified by Protein G affinity chromatography from culture supernatant.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rat
Immunogen:: Mouse ALK5 extra-cellular domain.
Klon:: 14L892
Format:: Supplied as a lyophilized powder in PBS. Reconstitute with 1000ul sterile PBS.
Weitere Details:: Overexpression of transforming growth factor ß1 in malignant prostate cells is partly caused by a runaway of TGF-ß1 auto induction mediated through a defective recruitment of protein phosphatase 2A by TGF-ß type I receptor. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:800-1:2000 Immunohistochemistry: 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.