216571
GITR (Glucocorticoid-induced TNFR-related Protein, Tumor Necrosis Factor Receptor Superfamily Member 18, TNFRSF18)
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£691.00
- SKU:
- 216571
- Reinheit:
- Purified by Protein G affinity chromatography from culture supernatant.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to human TNFRSF18
- Klon:
- 14L475
- Format:
- Supplied as a lyophilized powder in PBS. Reconstitute with 200ul sterile PBS.
- Weitere Details:
- This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. (provided by RefSeq, Feb 2011) Applications: Suitable for use in Neutralization, Flow Cytometry, and Western Blot. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:50-200 Western Blot: 1:500-1000 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice