Desmoglein 1 (Desmoglein-1, DSG1)

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£704.00

SKU:: 216451
Anwendung:: WB
Reinheit:: Purified by Protein G affinity chromatography from culture supernatant.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to human Desmoglein-1
Klon:: 14L355
Format:: Supplied as a lyophilized powder in PBS. Reconstitute with 200ul sterile PBS.
Weitere Details:: Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. DSG1 (Desmoglein 1) is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. DSG1 has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1000 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.