215268
Cyclin-Dependent Kinase Inhibitor 2A (Cyclin-dependent Kinase 4 Inhibitor A, CDK4I, p16-INK4a, p16INK4A, p16-INK4, Multiple Tumor Suppressor 1, MTS-1, CDKN2A, CDKN2, MTS1)
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£672.00
- SKU:
- 215268
- Reinheit:
- Purified
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to human Cyclin-dependent Kinase Inhibitor 2A.
- Klon:
- IMD-16
- Format:
- Supplied as a lyophilized powder in 1.2% sodium acetate, 2mg BSA, 0.01mg sodium azide. Reconstitute with 1ml PBS, pH 7.4.
- Weitere Details:
- The Cyclin-dependent kinase inhibitor 2A (CDK2NA) gene encodes several transcripts which differ from each other in their first exons. In spite of the structural and functional differences of these transcripts, they are all involved in cell cycle G1 control. Isoform 1, also known as p16INK4A, acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6 kinases. This antibody reacts specifically with this isoform (p16INK4A). Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.5-1ug/ml Immunohistochemistry (Formalin fixed and paraffin embedded tissues): 1-2ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice