215087
PLGF-1, Recombinant, Human (Placental Growth Factor1, PGFL, PLGF)
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£492.00
- SKU:
- 215087
- Molekulargewicht:
- 29.7
- Reinheit:
- ≥95% (SDS-PAGE, HPLC). Endotoxin: ≤0.1 ng/ug (<1EU/ug)
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Format:
- Supplied as a lyophilized powder from 10mM sodium phosphate. No preservative added. Reconstitute with sterile ddH2O to 0.1-1mg/ml. For extended storage, the additions of 0.1% bovine serum albumin (BSA) is recommended.
- Weitere Details:
- Placental growth factor (PLGF) is a dimeric glycoprotein and member of the vascular endothelial growth factor (VEGF) family, involved in angiogenesis, and the stimulation of endothelial cell proliferation and migration. The three isoforms PLGF-1, PLGF-2 and PLGF-3 are present in most placental tissues and act through binding to the VEGFR-1/FLT1 receptor. PLGF has become a focus area in the study of angiogenesis and inflammatory diseases such as rheumatoid arthritis and psoriasis, and PLGF is used as a biochemical marker in cardiovascular disease, and also detected at reduced levels during preeclampsia. Recombinant protein corresponding to human Placental Growth Factor expressed in E. coli Molecular Weight: ~29.7kD Amino Acid Sequence (Monomer): MLPAVPPQQW ALSAGNGSSE VEVVPFQEVW GRSYCRALER LVDVVSEYPS EVEHMFSPSC VSLLRCTGCC GDENLHCVPV ETANVTMQLL KIRSGDRPSY VELTFSQHVR CECRPLREKM KPERCGDAVP RR Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration range of 1-10ng/ml. Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice