208502
VAP1 (AOC3, Amine oxidase, Copper containing 3, Amine oxidase, Copper containing 3 (vascular adhesion protein 1), Copper amine oxidase, HPAO, Semicarbazide-sensitive amine oxidase, SSAO, VAP-1, Vascular adhesion protein 1)
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£642.00
- SKU:
- 208502
- Reinheit:
- Purified by immunoaffinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Goat
- Immunogen:
- Synthetic peptide corresponding to ESQAPKTIRDAFC, from the internal region of the protein sequence according to NP_003725.1. Species sequence homology: rat and mouse
- Format:
- Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
- Weitere Details:
- Vascular Adhesion Protein 1 (VAP-1), also called AOC3 (amine oxidase copper-containing 3) or SSAO (semicarbazide-sensitive amine oxidase) is a type II transmembrane sialoglycoprotein that is upregulated on endothelial cells by inflammation. The 170kD disulfide-linked homodimer of 763 aa units is an ectoenzyme that deaminates amines, forming aldehydes and hydrogen peroxide. It also mediates lymphocyte rolling, adhesion and possibly extravasation during inflammation. Adipocytes can release a soluble form via metalloproteinase cleavage. Human and mouse VAP-1 share 83% aa identity. Applications: Suitable for use in Peptide ELISA and Western Blot. Other applications not tested. Recommended Dilution: Peptide ELISA: 1:128,000 Western Blot: 0.1-0.3ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice