207495

ASAH1 (N-acylsphingosine Amidohydrolase (Acid ceramidase), 1AC, ASAH, FLJ21558, FLJ22079, PHP, PHP32)

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£685.00

SKU:: 207495
Reinheit:: Purified
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to aa25-124 with GST tag. MW of the GST tag alone is 26kD.
Klon:: 2C9
Format:: Supplied as a liquid in PBS, pH 7.4.
Weitere Details:: This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: PPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYKR WHELMLDKAPMLKVIVNSLKNMINTFVPSGKVMQVVD EKLPGLLGNFPGPFEEEMKGIAAVTD Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.