SLC1A5 (ATBO, ASCT2, ATB0, Baboon M7 Virus Receptor, AAAT, M7VS1, M7V1, R16, RDRC, RD114 Virus Receptor, RDR, ATB(0))

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£709.00

SKU:: 171254
Anwendung:: IHC-Fr
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 15aa from the C-terminus of human SLC1A5. Species sequence homology: gibbon, monkey and rat.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Weitere Details:: Solute Carrier Family 1 Member 5 (Slc1a5/ASCT2) belongs to a family of sodium dependent amino acid transporters. Slc1a5 has a preference for transporting zwitter ions. Slc1a5 also functions as a cell surface receptor for endogenously inherited retroviruses of cats, baboons and humans as well as for horizontally transmitted type-D simian retroviruses. In addition, it has been associated with increased metabolism in malignant tumors. In prostate carcinoma ASCT2 positivity is correlated with more aggressive biological behavior. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 2.5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.