CDK12 (Cyclin-dependent Kinase 12, Cdc2-related Kinase, Arginine/Serine-rich, CrkRS, Cell Division Cycle 2-related Protein Kinase 7, CDC2-related Protein Kinase 7, Cell Division Protein Kinase 12, hCDK12, CRK7, CRKRS, KIAA0904)

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£735.00

SKU:: 170284
Anwendung:: IHC-Fr
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 20aa from the internal region of human CDK12/CRKRS. Species sequence homology: rat, bat, bovine and rabbit.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Weitere Details:: CRK7 is a CDC2/CDK -type protein kinase. Also known as CRKRS, the protein has an arginine/serine-rich (RS) domain that is found predominantly in splicing factors, and extensive proline-rich regions that match the consensus for SH3 and WW domain binding sites. Anti-CrkRS immunoprecipitates have been shown to phosphorylate the C-terminal domain of RNA polymerase II in vitro. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 6ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.