168374
MLF1IP (CENP-U, CENP50, CENPU50, Centromere Protein U, ICEN24, KLIP1, Polo-box-interacting Protein 1, MLF1-interacting Protein, CENP-50, Centromere Protein of 50kD, MLF1 interacting Protein, MLF1IP, PBIP1)
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£914.00
- SKU:
- 168374
- Reinheit:
- Purified by immunoaffinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to 418 residues from human MLF1IP at C-terminus. Species sequence homology: chimpanzee, equine, bovine, canine, mouse, rat and chicken
- Format:
- Supplied as a liquid in 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2, 0.01% sodium azide.
- Weitere Details:
- Myeloid leukemia factor-1 (MLF1) Interacting protein, also known as PBIP1, is a novel gene that encodes a putative transcriptional repressor. It is localized to human chromosome 4q35.1, is expressed in both the nuclei and cytoplasm of cells, and is a novel substrate for polo-like kinase (PLK1). Phosphorylation by PLK1 regulates the PLK1-MLF1 interaction and localization to the kinetochores promoting proper chromosome segregation. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:650,000 Western Blot: 1:500-1:2000, expect a band ~65kD corresponding to MLF1IP protein in the appropriate cell lysate or extract. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice