IL22, Recombinant, Mouse (Interleukin-22, IL-22, IL-10-related T-cell-derived-inducible Factor, IL-TIF, IL-TIF alpha, Interleukin-22a, IL-22a, Il22a, Iltif, Iltifa)

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£351.00

SKU:: 149697
Reinheit:: ~98% (SDS-PAGE and HPLC)
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Format:: Supplied as a lyophilized powder.
Weitere Details:: IL-22 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their aa sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10R-beta/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family. Recombinant mouse IL-22 is a 33.4kD non-disulfide-linked homodimeric protein containing of two 146aa polypeptide chains. Source: Recombinant protein corresponding to mouse IL-22, expressed in E.coli. Biological Activity: Determined by its ability to activate STAT following receptor ligand interaction. Endotoxin: <0.1ng/ug (1EU/ug) AA Sequence: MLPVNTRCKL EVSNFQQPYI VNRTFMLAKE ASLADNNTDV RLIGEKLFRG VSAKDQCYLM KQVLNFTLED VLLPQSDRFQ PYMQEVVPFL TKLSNQLSSC HISGDDQNIQ KNVRRLKETV KKLGESGEIK AIGELDLLFM SLRNACV Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Versandbedingungen:: Blue Ice