Entacapone ((2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide)

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£267.00

SKU:: 145673
Molekulargewicht:: 305.29
Reinheit:: ~99% (HPLC)
Lagerbedingungen:: RT
Hersteller:: United States Biological
CAS Number:: 130929-57-6
Format:: Supplied as a yellow solid.
Weitere Details:: Potent catechol O-methyltransferase (COMT) inhibitor (IC50 values are 14.3, 20.1 and 73.3nm for rat liver soluble COMT, total COMT and membrane-bound COMT respectively). Increases bioavailability of levodopa when given as an adjunct therapy for Parkinson's disease. Inhibits alpha-synuclein aggregation in an in vitro assay; blocks alpha-synuclein-induced cell death in PC-12 cells. Formula: C14H15N3O5 Solubility: DMSO (~100mM), Ethanol (~10mM) Molecular Weight: ~305.29 Storage and Stability: Store at RT. Stable for 12 months.

Entacapone ((2E)-2-Cyano-3-(3,4-dihydroxy-5-nit­rophenyl)-N,N-diethyl-2-propenamide)