145662
AMG 548 (2-[[(2S)-2-Amino-3-phenylpropyl]amino]-3-methyl-5-(2-naphthalenyl)-6-(4-pyridinyl)-4(3H)-pyrimidinone)
Größe
£536.00
- SKU:
- 145662
- Molekulargewicht:
- 461.56
- Reinheit:
- ~98% (HPLC)
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- CAS Number:
- 864249-60-5
- Format:
- Supplied as a yellow solid.
- Weitere Details:
- Potent and selective inhibitor of p38alpha (Ki values are 0.5, 3.6, 2600 and 4100nm for p38a, p38beta, p38gamma and p38delta respectively). Displays >1000-fold selectivity against 36 other kinases; inhibits whole blood LPS-stimulated TNFalpha (IC50 = 3nm). Sequence: C29H27N5O.HCl Solubility: DMSO (~100mM), Ethanol (~100mM) Molecular Weight: ~461.56 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice