BIN1 (AMPHL, AMPH2, , SH3P9, amphiphysin II, Amphiphysin-like protein, Box-dependent myc-interacting protein 1, Bridging integrator 1)

Größe

£620.00

SKU:: 144238
Lagerbedingungen:: 4°C/-20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Recombinant polypeptide containing amino acids 189-398 of human Bin1.
Klon:: BN-1
Format:: Ascites, supplied as a lyophilized powder. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.
Weitere Details:: BIN1 (AMPH2) is a novel human gene product with features of a tumor suppressor protein. BIN1 gene to chromosome 2q14. Loss of BIN1 expression appears to be a frequent aberration in human hepatocellular carcinomas . mutations in BIN1 cause centronuclear myopathy by interfering with remodeling of T tubules and/or endocytic membranes, and that the functional interaction between BIN1 and DNM2 is necessary for normal muscle function and positioning of nuclei. UniProt Number: Human(O00499), Mouse(O08539), Rat(O08839) Gene ID: BIN1 Applications: Suitable for use in Western Blot, Immunohistochemistry (Frozen), and Immunocytochemistry. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Handling: Store at -20˚C for one year. After reconstitution, store at 4˚C for one month. Can also be aliquoted and stored frozen at -20˚C for long term. Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.